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What is this medicine
Zoloft (SER-tra-leen) is used to treat mental depression, obsessive-compulsive disorder, panic disorder and posttraumatic stress disorder.

Zoloft belongs to a group of medicines known as sele ctive serotonin reuptake inhibitors (SSRIs). These medicines are thought to work by increasing the activity of the chemical serotonin in the brain.

Adverse Effects
Central and Peripheral Nervous System Disorders: - Frequent: Confusion. Infrequent: Ataxia, abnormal coordination, abnormal gait, hyperesthesia, hyperkinesia, hypokinesia, migraine, nystagmus, vertigo . Rare: Local anesthesia, coma, convulsions, dyskinesia, dysphonia, hyporeflexia, hypotonia, ptosis.

Before Using This Medicine
Monoamine oxidase (MAO) inhibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], tranylcypromine [e.g., Parnate])¡X Do ot take Zoloft while you are taking or within 2 weeks of taking an MAO inhibitor. If you do, you may develop confusion, agitation, restlessness, stomach or intestinal symptoms, sudden high body temper ature, extremely high blood pressure, severe convulsions, or the serotonin syndrome. At least 14 days should be allowed between stopping treatment with one medicine (Zoloft or the MAO inhibitor) and s tarting treatment with the other

Management of Overdoses:

- hair loss
- changes in sex drive or ability
- drowsiness
- excessive tiredness
- difficulty falling asleep or staying asleep
- diarrhea
- vomiting
- rapid pou nding or irregular heartbeat
- upset stomach
- dizziness
- excitement
- tremor
- coma
- seizures
- hearing voices or seeing things that do not exist (hallucinating)
- unconsciousness
- fainting

Proper Use of This Medicine
Zoloft comes as a tablet and concentrate to take by mouth. It is usually taken once daily and may be taken with or without food. Follow the directions on your prescription label carefully, and ask you r doctor or pharmacist to explain any part you do not understand. Take Zoloft exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Continu e to take Zoloft even if you feel well. Do not stop taking Zoloft without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will want to decrease y our dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt.

What side effects can this medication cause?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zoloft.

Zoloft may also cause mental or emotional symptoms such as:
- Abnormal dreams or thoughts, aggressiveness, exaggerated feeling of well-being, depersonalization ("unreal" feeling), hallucinat ions, impaired concentration, memory loss, paranoia, rapid mood shifts, suicidal thoughts, tooth-grinding, worsened depression

Many people lose a pound or two of body weight while taking Zolo ft. This usually poses no problem but may be a concern if your depression has already caused you to lose a great deal of weight.


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