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Why is this drug prescribed?
Prozac , an antidepressant (mood elevator), is used to treat depression, obsessive-compulsive disorders, and some eating disorders. Prozac (Sarafem) is used to treat premenstrual dysphoric disorder.

Other medical problems
Older adults¡XMany medicines have not been tested in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effec s or problems in older people. In studies done to date that included elderly people, Prozac did not cause different side effects or problems in older people than it did in younger adults.

Drug Interactions
P450 isozyme (IID6): - Like other selective serotonin reuptake inhibitors, fluoxetine inhibits the specific hepatic cytochrome P450 isozyme (IID6) which is responsible for the metabolism of debrisoqui ne and sparteine. Although the clinical significance of this effect has not been established, inhibition of IID6 may lead to elevated plasma levels of co-administered drugs which are metabolized by th is isozyme. Drugs metabolized by cytochrome P450IID6 include the tricyclic antidepressants (e.g., nortriptyline, amitriptyline, imipramine, and desipramine), phenothiazine neuroleptics (e.g., perphena zine and thioridazine), and Type 1C antiarrhythmics (e.g., propafenone and flecainide).


Adverse Effects
Behavioral:
Frequent: Insomnia, anxiety, nervousness, agitation, abnormal dreams, drowsiness and fatigue.

Infrequent: Confusion, delusions, hallucinations, manic reaction, paranoid react ion, psychosis, depersonalization, apathy, emotional lability, euphoria, hostility, amnesia, increased libido.

Rare: Antisocial reaction, hysteria, suicidal ideation, violent behaviors.

How to Use
Prozac should be taken exactly as prescribed by your doctor.

Prozac usually is taken once or twice a day. To be effective, it should be taken regularly. Make a habit of taking it at the same time you do some other daily activity.

It may be 4 weeks before you feel any relief from your depression, but the drug's effects should last about 9 months after a 3-month treatment regimen . For obsessive-compulsive disorder, the full effect may take 5 weeks to appear.

What side effects may occur?
Check with your doctor as soon as possible if any of the following side effects occur:

- Decreased sexual drive or ability; inability to sit still; restlessness; skin rash, hives, or itchi ng

- Chills or fever; joint or muscle pain

- Breast enlargement or pain; convulsions (seizures); fast or irregular heartbeat; purple or red spots on skin; symptoms of hypog lycemia (low blood sugar), including anxiety or nervousness, chills, cold sweats, confusion, cool pale skin


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